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Evidence: Clinical study
Logical Profile #gingGinger Rhizome
Zingiber officinale
Mechanism of Action
"5-HT3 receptor antagonism in the chemoreceptor trigger zone; inhibits cyclooxygenase and lipoxygenase pathways in inflammatory tissue."
Active Compounds
6-Gingerol
8-Gingerol
6-Shogaol
Zingerone
Tissue Affinity
Gastrointestinal tract, Peripheral nociceptors, Platelets
Medical Indications
Chemotherapy/pregnancy nausea, delayed gastric emptying, migraine, dysmenorrhea
Dosage Logic
1,000mg dried rhizome powder daily or standardized supercritical CO2 extract for systemic joint stiffness.
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Drug Interactions
Anticoagulants at mega-doses (>4g daily)
Contraindications
Active cholelithiasis, Peptic ulcer exacerbation