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Evidence: Clinical study
Logical Profile #ginkGinkgo Biloba
Ginkgo biloba
Mechanism of Action
"Competitive antagonism of Platelet-Activating Factor (PAF); enhances nitric oxide-mediated microvascular vasodilation."
Active Compounds
Ginkgolides A, B, C
Bilobalide
Quercetin glycosides
Kaempferol
Tissue Affinity
Cerebral microvasculature, Inner ear labyrinth, Retinal capillaries
Medical Indications
Cerebrovascular insufficiency, tinnitus, peripheral arterial disease, executive memory
Dosage Logic
Standardized EGb 761 extract (24% flavone glycosides, 6% terpene lactones) at 120-240mg daily in divided doses.
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Drug Interactions
Warfarin, Aspirin, Clopidogrel, NSAIDs (elevated hemorrhage risk)
Contraindications
Pre-operative bleeding diathesis (stop 7 days prior to surgery)